First Outbreak The first herpes outbreak often occurs within the 2 weeks after contracting the virus from an infected person. The first signs may include: Itching, tingling, or burning feeling in the vaginal or anal area. Flu-like symptoms, including fever.

Is herpes worse for females?

Symptoms of genital herpes tend to be worse in women. These typically include blisters that become painful sores. Some infected women also experience an unusual vaginal discharge.