Absolutely nothing, and thats part of the point of The 40-Year-Old Virgin, probably the most sweet-spirited sex comedy ever made. Its pretty funny, too. He went on to call the lead character endearing and a marvelous comic invention.

Is The 40-Year-Old Virgin a good movie?

Heres a movie that could have had the same title and been a crude sex comedy with contempt for its characters. Instead, The 40-Year-Old Virgin is surprisingly insightful, as buddy comedies go, and it has a good heart and a lovable hero.